Children:
- William Alexander, Sr. was born about 1646 in Raphoe, Co. Donegal, Ulster, Ireland; died between 1707 and 1715 in Manokin Hundred, Somerset County, Maryland.
- Andrew Alexander, (the farmer) was born about 1648 in Raphoe, Co. Donegal, Ulster, Ireland; died before 1700 in Somerset Co., MD.
- Elizabeth Alexander was born about 1650 in Raphoe, Co. Donegal, Ulster, Ireland; died about 1716 in Manokin Hundred, Somerset Co., Maryland Colony.
- James Alexander, (the weaver) was born about 1650 in Raphoe, Co. Donegal, Ulster, Ireland; died in 1717 in New Munster Manor, Cecil Co., MD.
- Francis Alexander was born about 1654 in Raphoe, Co. Donegal, Ulster, Ireland; died after 1719 in New Munster Manor, Cecil Co. MD.
- 4. Samuel Alexander was born about 1657 in Raphoe, Co. Donegal, Ulster, Ireland; died on 14 Jun 1733 in New Munster Manor, Cecil Co. MD.
- Joseph Alexander, (the Tanner) was born about 1660 in Raphoe, Co. Donegal, Ulster, Ireland; died before 9 Mar 1730 in New Munster Manor, Cecil Co. MD.
- John Alexander, (the Carpenter) was born about 1662 in Raphoe, Co. Donegal, Ulster, Ireland; died after 1718 in New Munster, Cecil Co., MD.
- Jane Alexander was born about 1665 in Raphoe, Co. Donegal, Ulster, Ireland; died on 28 Mar 1692 in Manokin Hundred, Somerset Co., Maryland Colony.
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